
Database and registry-based identification strategies
Translate eligibility criteria into EHR queries, manage false positives, leverage research registries, and apply data governance principles for population-level participant identification.
1.2 million records and 50 needles
The site's electronic health record system contains 1.2 million patient records. Somewhere in that population are approximately 50 people who meet every eligibility criterion for the Phase III diabetes trial that just received IRB approval. The protocol requires adults aged 40 to 75 with a confirmed diagnosis of Type 2 diabetes mellitus, HbA1c between 7.5% and 10.5% within the past 90 days, on stable metformin monotherapy for at least 12 weeks, with an estimated glomerular filtration rate above 45 mL/min/1.73m2. And that is before the exclusion criteria β no recent cardiovascular events, no active malignancy, no current insulin use, no pregnancy or nursing.